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Article

Zebrafish as a novel model to assess Na+/K(+)-ATPase-related neurological disorders.

Neuroscience and biobehavioral reviews - 1 Dec 2013

Doğanli Canan, Oxvig Claus, Lykke-Hartmann Karin

Abstract excerpt

Modeling neurological disorders using zebrafish increases rapidly as this model system allows easy access to all developmental stages and imaging of pathological processes. A surprising degree of functional conservation has been demonstrated between human genes implicated in neurodegenerative diseases and their zebrafish orthologues. Zebrafish offers rapid high throughput screening of therapeutic compounds and...

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PMID: 24091024
DOI: 10.1016/j.neubiorev.2013.09.013

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