Article

<i>SSD1</i> suppresses phenotypes induced by the lack of Elongator-dependent tRNA modifications

2019-04-01

Abstract excerpt

The Elongator complex promotes formation of 5-methoxycarbonylmethyl (mcm 5 ) and 5-carbamoylmethyl (ncm 5 ) side-chains on uridines at the wobble position of cytosolic eukaryotic tRNAs. In all eukaryotic organisms tested to date, the inactivation of Elongator not only leads to the lack of mcm 5 /ncm 5 groups in tRNAs, but also a wide variety of phenotypes. Although the phenotypes are most likely caused by a tr...

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Literature Corpus work: 8a34bcdb-9e35-5bfa-9d6a-b31bbf715a4b
DOI: 10.1101/596197

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