Article
tRNA thiolation links translation to stress responses in Saccharomyces cerevisiae.
Molecular biology of the cell - 15 Jan 2015
Damon Jadyn R, Pincus David, Ploegh Hidde L
Abstract excerpt
Although tRNA modifications have been well catalogued, the precise functions of many modifications and their roles in mediating gene expression are still being elucidated. Whereas tRNA modifications were long assumed to be constitutive, it is now apparent that the modification status of tRNAs changes in response to different environmental conditions. The URM1 pathway is required for thiolation of the cytoplasmic...
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