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Article

An early step in wobble uridine tRNA modification requires the Elongator complex.

RNA (New York, N.Y.) - 1 Apr 2005

Huang Bo, Johansson Marcus J O, Byström Anders S

Abstract excerpt

Elongator has been reported to be a histone acetyltransferase complex involved in elongation of RNA polymerase II transcription. In Saccharomyces cerevisiae, mutations in any of the six Elongator protein subunit (ELP1-ELP6) genes or the three killer toxin insensitivity (KTI11-KTI13) genes cause s...

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Source

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Identifiers

PMID: 15769872
DOI: 10.1261/rna.7247705
PMCID: PMC1370732

Genes

ELP1
ELP6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15769872-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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An early step in wobble uridine tRNA modification requires the Elongator complex.PMID 15769872Read ↗

Elevated levels of two tRNA species bypass the requirement for elongator complex in transcription and exocytosis.Semantic proximity Read ↗

Elongator complex influences telomeric gene silencing and DNA damage response by its role in wobble uridine tRNA modification.Semantic proximity Read ↗

SSD1 modifies phenotypes of Elongator mutants.Semantic proximity Read ↗

Nuclear surveillance and degradation of hypomodified initiator tRNAMet in S. cerevisiae.Semantic proximity Read ↗

Phosphorylation of Elp1 by Hrr25 is required for elongator-dependent tRNA modification in yeast.Semantic proximity Read ↗

Novel methyltransferase for modified uridine residues at the wobble position of tRNA.Semantic proximity Read ↗

<i>SSD1</i> suppresses phenotypes induced by the lack of Elongator-dependent tRNA modificationsSemantic proximity Read ↗

Loss of Elongator- and KEOPS-Dependent tRNA Modifications Leads to Severe Growth Phenotypes and Protein Aggregation in Yeast.Semantic proximity Read ↗

Elongator-dependent modification of cytoplasmic tRNALysUUU is required for mitochondrial function under stress conditions.Semantic proximity Read ↗

Initiator tRNA lacking 1-methyladenosine is unexpectedly targeted by the rapid tRNA decay pathway in evolutionarily distant yeast speciesSemantic proximity Read ↗

Rit1, a tRNA backbone-modifying enzyme that mediates initiator and elongator tRNA discrimination.Semantic proximity Read ↗

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