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Article

SSD1 modifies phenotypes of Elongator mutants.

Current genetics - 1 Jun 2020

Xu Fu, Byström Anders S, Johansson Marcus J O

Abstract excerpt

The translational decoding properties of tRNAs are influenced by post-transcriptional modification of nucleosides in their anticodon region. The Elongator complex promotes the first step in the formation of 5-methoxycarbonylmethyl (mcm5), 5-methoxycarbonylhydroxymethyl (mchm5), and 5-carbamoylmethyl (ncm5) groups on wobble uridine residues in eukaryotic cytosolic tRNAs. Elongator mutants in yeast, worms, plants,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31776648
DOI: 10.1007/s00294-019-01048-9
PMCID: PMC7198479

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