Back to search

Article

Multi-center integrated analysis of non-coding CRISPR screens

2022-12-22

Abstract excerpt

The ENCODE Consortium’s efforts to annotate non-coding, cis -regulatory elements (CREs) have advanced our understanding of gene regulatory landscapes which play a major role in health and disease. Pooled, non-coding CRISPR screens are a promising approach for systematically investigating gene regulatory mechanisms. Here, the ENCODE Functional Characterization Centers report 109 screens comprising 346,970 individu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
8a25f2d8-68a0-5cd5-8902-16b29b26409f
DOI
10.1101/2022.12.21.520137
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Multi-center integrated analysis of non-coding CRISPR screensDOI 10.1101/2022.12.21.520137
Select a neighboring publication to make it the new centre.