Article

Cryo-EM Structure of Native Human Uromodulin, a Zona Pellucida Module Polymer

2020-05-28

Abstract excerpt

<h4>SUMMARY</h4> Assembly of extracellular filaments and matrices mediating fundamental biological processes such as morphogenesis, hearing, fertilization and antibacterial defense is driven by a ubiquitous polymerization module known as zona pellucida (ZP) “domain”. Despite the conservation of this element from hydra to human, no information is available on the filamentous conformation of any ZP module protein....

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Literature Corpus work: 8a2511ad-2ebc-56eb-b3a8-1cfe9331ae0d
DOI: 10.1101/2020.05.28.119206

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