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Article

A Structural View of Egg Coat Architecture and Function in Fertilization1

30 Jun 2011

Abstract excerpt

Species-restricted interaction between gametes at the beginning of fertilization is mediated by the extracellular coat of the egg, a matrix of cross-linked glycoprotein filaments called the zona pellucida (ZP) in mammals and the vitelline envelope in nonmammals. All egg coat subunits contain a conserved protein-protein interaction module-the "ZP domain"-that allows them to polymerize upon dissociation of a...

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Identifiers

PMID: 21715714
DOI: 10.1095/biolreprod.111.092098

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