Article

The ATPase cycle of Human Muscle Myosin II Isoforms: Adaptation of a single mechanochemical cycle for different physiological roles

2019-06-14

Abstract excerpt

Striated muscle myosins are encoded by a large gene family in all mammals, including human. These isoforms define several of the key characteristics of the different striated muscle fiber types including maximum shortening velocity. We have previously used recombinant isoforms of the motor domains of eight different human myosin isoforms to define the actin.myosin cross-bridge cycle in solution. Here, we use a rec...

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Literature Corpus work: 88b9f587-51e1-5ff5-be8d-3c0f00e6e6b6
DOI: 10.1101/672030

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