Article

Divergent spontaneous antibiotic-resistance evolution confers reciprocal and exploitable collateral sensitivity effects

2025-09-22

Abstract excerpt

The global rise of antibiotic-resistant pathogens has outpaced the development of new antibiotics, prompting the urgent need for alternative treatment strategies. One such approach is to leverage collateral sensitivity (CS), where resistance to one antibiotic increases susceptibility to another. However, the clinical implementation of CS-based therapies depends on the consistency of these responses, which is chall...

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Identifiers and source

Literature Corpus work: 88216097-542b-5860-ad9b-2348a352daef
DOI: 10.1101/2025.09.22.677096

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