Article

Conserved collateral susceptibility networks in diverse clinical strains of <i>Escherichia coli</i>

2018-01-17

Abstract excerpt

There is urgent need to develop novel treatment strategies to reduce antimicrobial resistance. Collateral sensitivity (CS), where resistance to one antimicrobial increases susceptibility to other drugs, is a uniquely promising strategy that enables selection against resistance during treatment. However, using CS-informed therapy depends on conserved CS networks across genetically diverse bacterial strains. We exam...

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Literature Corpus work: 5d3b034c-dfae-5791-be28-ccf388279b21
DOI: 10.1101/248872

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