Article

Coronary Artery Disease Risk Variant rs6903956 Links to Endothelial Dysfunction via <i>PHACTR1</i> Regulation

2025-05-15

Abstract excerpt

Ischemic heart disease, particularly coronary artery disease (CAD), remain leading causes of mortality worldwide. The single nucleotide polymorphism rs6903956 on chromosome 6p24.1 has been identified as a susceptibility locus for CAD in East Asian populations through genome-wide association studies. However, its functional role has not been fully elucidated. This study investigates the mechanistic basis of rs69039...

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Literature Corpus work: 87854706-ed18-5242-a93f-5d0648a9c0a9
DOI: 10.1101/2025.05.11.653298

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