Article

<i>Trans</i> -interaction of risk loci 6p24.1 and 10q11.21 is associated with endothelial damage in coronary artery disease

2022-07-13

Abstract excerpt

<h4>Background and Aims</h4> Single nucleotide polymorphism rs6903956 has been identified as one of the genetic risk factors for coronary artery disease (CAD). However, rs6903956 lies in a non-coding locus on chromosome 6p24.1. We aim to interrogate the molecular basis of 6p24.1 containing rs6903956 risk alleles in endothelial disease biology. <h4>Methods and Results</h4> We generated induced pluripotent stem ce...

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Literature Corpus work: 83f71228-f921-59a4-bb24-618bcd9aadff
DOI: 10.1101/2022.07.12.499721

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