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Article

Myocardial Infarction-Associated SNP at 6p24 Interferes With MEF2 Binding and Associates With PHACTR1 Expression Levels in Human Coronary Arteries.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2015

Beaudoin Mélissa, Gupta Rajat M, Won Hong-Hee, Lo Ken Sin, Do Ron, Henderson Christopher A, Lavoie-St-Amour Claire, Langlois Simon, Rivas Daniel, Lehoux Stephanie, Kathiresan Sekar, Tardif Jean-Claude, Musunuru Kiran, Lettre Guillaume

Abstract excerpt

OBJECTIVE: Coronary artery disease (CAD), including myocardial infarction (MI), is the main cause of death in the world. Genome-wide association studies have identified dozens of single nucleotide polymorphisms (SNPs) associated with CAD/MI. One of the most robust CAD/MI genetic associations is w...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25838425
DOI: 10.1161/ATVBAHA.115.305534
PMCID: PMC4441556

Genes

PHACTR1
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25838425-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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