Article

How group structure impacts the numbers at risk for coronary artery disease: polygenic risk scores and non-genetic risk factors in the UK Biobank cohort

2023-08-01

Abstract excerpt

The UK Biobank is a large cohort study that recruited over 500,000 British participants aged 40-69 in 2006-2010 at 22 assessment centres from across the UK. Self-reported health outcomes and hospital admission data are two types of records that include participants’ disease status. Coronary artery disease (CAD) is the most common cause of death in the UK Biobank cohort. After distinguishing between prevalence and...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8705d647-bed4-5aac-af30-5d76cc73bd1f
DOI: 10.1101/2023.07.28.23292953

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

How group structure impacts the numbers at risk for coronary artery disease: polygenic risk scores and non-genetic risk factors in the UK Biobank cohortDOI 10.1101/2023.07.28.23292953Read

How group structure impacts the numbers at risk for coronary artery disease: polygenic risk scores and nongenetic risk factors in the UK Biobank cohort.Semantic proximity Read

Comparison of polygenic risk scores for coronary artery disease highlights obstacles to overcome for clinical useSemantic proximity Read

Reproducible disease phenotyping at scale: Example of coronary artery disease in UK Biobank.Semantic proximity Read

Development of an Integrated Monogenic and Polygenic Risk Assessment Tool for Coronary Artery Disease and Its Application in a Community-Based Health Care Biobank.Semantic proximity Read

Population Bias in Polygenic Risk Prediction Models for Coronary Artery Disease.Semantic proximity Read

Associations of Blood Lipid-Related Polygenic Scores, Lifestyle Factors and Their Combined Effects with Risk of Coronary Artery Disease in the UK Biobank Cohort.Semantic proximity Read

A framework for integrated clinical risk assessment using population sequencing dataSemantic proximity Read

Polygenic Risk Score Modifies Risk of Coronary Artery Disease Conferred by Low-Density Lipoprotein CholesterolSemantic proximity Read

An integrated polygenic and clinical risk tool enhances coronary artery disease predictionSemantic proximity Read

Integrated Polygenic Tool Substantially Enhances Coronary Artery Disease Prediction.Semantic proximity Read

Association of Genetically Predicted Levels of Circulating Blood Lipids with Coronary Artery Disease IncidenceSemantic proximity Read

Validation of genome-wide polygenic risk scores for coronary artery disease in French CanadiansSemantic proximity Read