Article

Comparison of polygenic risk scores for coronary artery disease highlights obstacles to overcome for clinical use

2020-08-10

Abstract excerpt

Polygenic risk scores, or PRS, are a tool to estimate individuals’ liabilities to a disease or trait measurement based solely on genetic information. One commonly discussed potential use is in the clinic to identify people who are at greater risk of developing a disease. In this paper, we compare three PRS models that incorporate a large number of genetic markers for coronary artery disease (CAD). In the UK Bioban...

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Literature Corpus work: 2d6fe4aa-2dc2-5483-8b62-13308343658a
DOI: 10.1101/2020.08.09.243287

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