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Cell-autonomous BMP signalling plays a key role in the maintenance of tumour cell EMT and migration programs in human ovarian carcinoma

2023-04-30

Abstract excerpt

Epithelial-mesenchymal transition (EMT) plays a key role in tumour initiation, metastasis and resistance to therapy. Cells undergoing EMT, assume multiple semi-stable transitional states along the epithelial-mesenchymal axis that necessitates tight regulatory cascades. Although more is known about pathways involved in the initial induction of EMT, cascades that mediate/maintain the transitional states and/or the f...

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Literature Corpus work
86ad0721-6fb4-5ba5-ac36-8ed49aaf8e88
DOI
10.1101/2023.04.30.538847
Open publication

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Cell-autonomous BMP signalling plays a key role in the maintenance of tumour cell EMT and migration programs in human ovarian carcinomaDOI 10.1101/2023.04.30.538847
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