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Article

Propranolol inhibits EMT and metastasis in breast cancer through miR-499-5p-mediated Sox6

31 Jan 2024

Abstract excerpt

PURPOSE: This study will focus on 4T1 cells, a murine mammary adenocarcinoma cell line, as the primary research subject. We aim to investigate the inhibitory effects and mechanisms of propranolol on epithelial-mesenchymal transition (EMT) in breast cancer cells, aiming to elucidate this phenomenon at the miRNA level. METHODS: In this study, the EMT inhibitory effect of propranolol was observed through in vitro...

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PMID: 38294713
DOI: 10.1007/s00432-023-05599-w

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