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The Dual Role of Bone Morphogenetic Proteins in Cancer

23 Oct 2017

Abstract excerpt

Bone morphogenetic proteins (BMPs) are a diverse class of molecules with over 20 growth factor proteins that belong to the transforming growth factor-β (TGF-β) family and are highly associated with bone formation and disease development. Aberrant expression of various BMPs has been reported in several cancer tissues. Biological function studies have elicited the dual role of BMPs in both cancer development and...

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PMID: 29234727
DOI: 10.1016/j.omto.2017.10.002

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