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Bone morphogenetic proteins in breast cancer: dual role in tumourigenesis?

24 Mar 2010

Abstract excerpt

The human bone morphogenetic protein (BMP) family consists of over 20 growth factor proteins that are involved in bone formation and developmental processes. BMPs are extracellular signalling molecules that are able to regulate various cellular functions, proliferation, differentiation, apoptosis and migration. For the last 10 years, these powerful cytokines have increasingly been studied in several cancers, and...

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PMID: 20335308
DOI: 10.1677/erc-09-0273

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