Article
Gene expression differences among primates are associated with changes in a histone epigenetic modification.
Genetics - 1 Apr 2011
Cain Carolyn E, Blekhman Ran, Marioni John C, Gilad Yoav
Abstract excerpt
Changes in gene regulation are thought to play an important role in speciation and adaptation, especially in primates. However, we still know relatively little about the mechanisms underlying regulatory evolution. In particular, the extent to which epigenetic modifications underlie gene expression differences between primates is not yet known. Our study focuses on an epigenetic histone modification, H3K4me3,...
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