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Article

Regional DNA methylation differences between humans and chimpanzees are associated with genetic changes, transcriptional divergence and disease genes.

Journal of human genetics - 1 Jul 2013

Fukuda Kei, Ichiyanagi Kenji, Yamada Yoichi, Go Yasuhiro, Udono Toshifumi, Wada Seitaro, Maeda Toshiyuki, Soejima Hidenobu, Saitou Naruya, Ito Takashi, Sasaki Hiroyuki

Abstract excerpt

Changes in gene expression have been proposed to have an important role in the evolutionary changes in phenotypes. Interspecific changes in gene expression can result not only from genetic changes in regulatory regions but also from epigenetic changes in such regions. Here we report the identification of genomic regions showing differences in DNA methylation between humans and chimpanzees (termed S-DMRs for...

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PMID: 23739127
DOI: 10.1038/jhg.2013.55

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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