Article

Cancers with kinase fusion exhibit fewer actionable alterations than those with kinase mutation and amplification

2023-08-28

Abstract excerpt

<h4>Background: </h4> Kinase-related gene fusion and point mutations are important drivers, and optimized targeted therapy against these alterations is required. The effects of molecularly targeted therapeutics vary depending on the alteration, and such therapeutics have achieved their greatest success when used to treat chronic myelogenous leukemia with kinase fusion protein. In this study, we aimed to compare th...

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Literature Corpus work: 8633eaee-6187-543d-bfc1-a9235bdc9c4a
DOI: 10.21203/rs.3.rs-3171998/v1

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