Article

Comparison of actionable alterations in cancers with kinase fusion, mutation, and amplification

2024-05-25

Abstract excerpt

Kinase-related gene fusion and point mutations play pivotal roles as drivers in cancer, necessitating optimized targeted therapy against these alterations. The efficacy of molecularly targeted therapeutics varies depending on the specific alteration, with great success reported for such therapeutics in the treatment of cancer with kinase fusion proteins. However, the involvement of actionable alterations in solid...

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Literature Corpus work: 0b1451cd-0976-594e-982b-dbc1068024ef
DOI: 10.1101/2024.05.24.24307868

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