Article
Genomic characterization and outcome evaluation of kinome fusions in lung cancer revealed novel druggable fusions
10 Sept 2021
Abstract excerpt
Kinase fusions represent an important type of somatic alterations that promote oncogenesis and serve as diagnostic markers in lung cancer. We aimed to identify the landscape of clinically relevant kinase fusions in Chinese lung cancer and to explore rare kinase rearrangements; thus, providing valuable evidence for therapeutic decision making. We performed genomic profiling of 425 cancer-relevant genes from...
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