Article

Evolution and genomic signatures of spontaneous somatic mutation in <i>Drosophila</i> intestinal stem cells

2020-07-20

Abstract excerpt

Spontaneous mutations can alter tissue dynamics and lead to cancer initiation. While large-scale sequencing projects have illustrated processes that influence somatic mutation and subsequent tumour evolution, the mutational dynamics operating in the very early stages of cancer development are currently not well understood. In order to explore mutational dynamics in the early stages of cancer evolution we exploited...

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Literature Corpus work: 854beaa9-0c9b-596e-9db0-c9b597951f6d
DOI: 10.1101/2020.07.20.188979

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