Article
More Frequent than Desired: Midgut Stem Cell Somatic Mutations.
Cell stem cell - 3 Dec 2015
Li Qi, Ip Y Tony
Abstract excerpt
The accumulation of somatic mutations in adult stem cells contributes to the decline of tissue functions and cancer initiation. In this issue of Cell Stem Cell, Siudeja et al. (2015) investigate the rate and mechanism of naturally occurring mutations in Drosophila midgut intestinal stem cells during aging and find high-frequency mutations arising from multiple mechanisms.
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