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Somatic transposition in the <i>Drosophila</i> intestine occurs in active chromatin and is associated with tumor suppressor gene inactivation

2020-07-10

Abstract excerpt

Transposable elements (TEs) play a significant role in evolution by contributing to genetic variation through germline insertional activity. However, how TEs act in somatic cells and tissues is not well understood. Here, we address the prevalence of transposition in a somatic tissue, exploiting the Drosophila midgut as a model system. Using whole-genome sequencing of in vivo clonally expanded gut tissue, we map...

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Literature Corpus work
d59d20c4-909f-5aae-b25c-a6026739cd7a
DOI
10.1101/2020.07.10.166629
Open publication

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Somatic transposition in the <i>Drosophila</i> intestine occurs in active chromatin and is associated with tumor suppressor gene inactivationDOI 10.1101/2020.07.10.166629
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