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Generation of Skeletal Muscle Organoids from Human Pluripotent Stem Cells

1 Jan 2024

Abstract excerpt

Various protocols have been proven effective in the directed differentiation of mouse and human pluripotent stem cells into skeletal muscles and used to study myogenesis. Current 2D myogenic differentiation protocols can mimic muscle development and its alteration under pathological conditions such as muscular dystrophies. 3D skeletal muscle differentiation approaches can, in addition, model the interaction...

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PMID: 38737507
DOI: 10.21769/bioprotoc.4984

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