Article

Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors

2020-09-14

Abstract excerpt

In vitro culture systems that structurally model human myogenesis and promote PAX7 + myogenic progenitor maturation have not been established. Here we report that human skeletal muscle organoids can be differentiated from induced pluripotent stem cell lines to contain paraxial mesoderm and neuromesodermal progenitors and develop into organized structures reassembling neural plate border and dermomyotome. Culture...

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Literature Corpus work: 1c2d6ef7-c55a-5686-a3a9-bc16e18f0806
DOI: 10.1101/2020.09.14.295832

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