Article

Cardiopharyngeal Mesoderm specification into cardiac and skeletal muscle lineages in gastruloids

2023-05-15

Abstract excerpt

Cardiopharyngeal mesoderm contributes to the formation of the heart and head muscles. However, the mechanisms governing cardiopharyngeal mesoderm specification remain unclear. Indeed, there is a lack of an in vitro model replicating the differentiation of both heart and head muscles to study these mechanisms. Such models are required to allow live-imaging and high throughput genetic and drug screening. Here, we s...

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Literature Corpus work: 44ddc557-b4b5-5908-9982-35f2087584be
DOI: 10.1101/2023.05.15.540476

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