Article

Folate stress as a Contributing Factor to Fanconi Anemia

2026-01-22

Abstract excerpt

<title>Abstract</title> <p> Fanconi Anemia (FA) is a rare chromosomal instability disorder characterized by progressive bone marrow failure, congenital abnormalities, and a heightened cancer predisposition. With at least 22 identified FA genes, biallelic mutations in any one of these genes disrupt the FA pathway, a specialized DNA repair mechanism, leading to disease pathogenesis. FA cells are hypersensitive to...

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Literature Corpus work: 84e840cd-d3a5-5e3f-affd-b9340a416007
DOI: 10.21203/rs.3.rs-8498123/v1

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