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Article

Multifaceted Fanconi Anemia Signaling.

Trends in genetics : TIG - 1 Mar 2018

Che Raymond, Zhang Jun, Nepal Manoj, Han Bing, Fei Peiwen

Abstract excerpt

In 1927 Guido Fanconi described a hereditary condition presenting panmyelopathy accompanied by short stature and hyperpigmentation, now better known as Fanconi anemia (FA). With this discovery the genetic and molecular basis underlying FA has emerged as a field of great interest. FA signaling is crucial in the DNA damage response (DDR) to mediate the repair of damaged DNA. This has attracted a diverse range of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29254745
DOI: 10.1016/j.tig.2017.11.006
PMCID: PMC5858900

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