Article

Genetic Profiling of Autoimmune Diseases and Exploring Clusters Through Polygenic Risk Score Analysis Using Cohort Data from the UK Biobank

2026-05-13

Abstract excerpt

Autoimmune diseases result from immune responses against self-antigens but exhibit marked phenotypic diversity shaped by genetic and environmental factors. Genome-wide association studies (GWAS) have identified susceptibility loci that inform polygenic scores (PGS) for risk prediction. This study integrates phenotypic and genetic data from the UK Biobank(UKB) to characterize disease overlap, genetic heterogeneity,...

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Literature Corpus work: 84c0dc1d-514d-5950-9c0b-f183ffb2c412
DOI: 10.64898/2026.05.09.26352677

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