Article

Mapping the genetic landscape of disorders on the autoimmune-autoinflammatory continuum: potential implications for classification and treatment

2024-08-08

Abstract excerpt

<h4>Objectives</h4> Based on clinical, biomarker and genetic data, autoimmune and autoinflammatory disorders (AIDs) can be classified as a disease continuum from pure autoinflammatory to pure autoimmune with mixed diseases in between. However, the genetic architecture of AIDs has not been systematically described. Here we investigate the polygenic continuum of AIDs using genome-wide association studies (GWAS) and...

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Literature Corpus work: 6ff0f0bf-2457-54e2-b8bb-14313c83ae6c
DOI: 10.1101/2024.08.08.24311518

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