Article
Common genetic factors among autoimmune diseases.
Science (New York, N.Y.) - 5 May 2023
Harroud Adil, Hafler David A
Abstract excerpt
Autoimmune diseases display a high degree of comorbidity within individuals and families, suggesting shared risk factors. Over the past 15 years, genome-wide association studies have established the polygenic basis of these common conditions and revealed widespread sharing of genetic effects, indicative of a shared immunopathology. Despite ongoing challenges in determining the precise genes and molecular...
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