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An important role of the interplay between <i>Bdnf</i> transcription and histone acetylation in epileptogenesis

2020-09-01

Abstract excerpt

Brain-Derived Neurotrophic Factor is one of the most important trophic proteins in the brain. The role of this growth factor in neuronal plasticity, in health and disease, has been extensively studied. However, mechanisms of epigenetic regulation of Bdnf gene expression in epilepsy are still elusive. In our previous work, using a rat model of neuronal activation upon kainate-induced seizures, we observed a reposi...

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Literature Corpus work
84543c17-5b72-5822-9079-e4e297874ecb
DOI
10.1101/2020.09.01.277327
Open publication

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An important role of the interplay between <i>Bdnf</i> transcription and histone acetylation in epileptogenesisDOI 10.1101/2020.09.01.277327
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