Role of brain-derived neurotrophic factor and NF-kappaB in neuronal plasticity and survival: From genes to phenotype.

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Article

Role of brain-derived neurotrophic factor and NF-kappaB in neuronal plasticity and survival: From genes to phenotype.

Restorative neurology and neuroscience - 1 Jan 2004

Marini Ann M, Jiang Xueying, Wu Xuan, Tian Feng, Zhu Daming, Okagaki Peter, Lipsky Robert H

Abstract excerpt

PURPOSE: Brain-derived neurotrophic factor (BDNF) is a member of the family of neurotrophins and promotes diverse effects in neurons including development, maintenance of function, synaptic plasticity, and survival in different animal models. We present advances in our understanding of the genomics of the BDNF gene (bdnf) and its regulation by calcium-activated transcription factors, including cAMP response...

Topics

Animals
Base Sequence
Brain-Derived Neurotrophic Factor
Cell Survival
Humans
Molecular Sequence Data
NF-kappa B
Neuronal Plasticity
Neurons
Phenotype

Source

Open in PubMed

Identifiers

PMID: 15272146

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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