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Article

MK-801, a NMDA receptor antagonist, increases phosphorylation of histone H3 in the rat medial prefrontal cortex.

Pharmacological reports : PR - 1 Jan 2013

Maćkowiak Marzena, Guzik Rafał, Dudys Dorota, Bator Ewelina, Wędzony Krzysztof

Abstract excerpt

BACKGROUND: The present study investigated whether MK-801, when given in doses that cause psychomimetic effects in rats, could alter the phosphorylation of histone 3 (H3) at serine 10 (H3S10p) and the acetylation of H3 at lysine 14 (H3K14ac) in the medial prefrontal cortex (mPFC). These posttrans...

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Source

Identifiers

PMID: 24399707
DOI: 10.1016/s1734-1140(13)71469-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24399707-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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