Article

Plxnd1-mediated mechanosensing of blood flow controls the caliber of the Dorsal Aorta via the transcription factor Klf2

2024-01-25

Abstract excerpt

<h4>SUMMARY</h4> The cardiovascular system generates and responds to mechanical forces. The heartbeat pumps blood through a network of vascular tubes, which adjust their caliber in response to the hemodynamic environment. However, how endothelial cells in the developing vascular system integrate inputs from circulatory forces into signaling pathways to define vessel caliber is poorly understood. Using vertebrate...

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Literature Corpus work: 8409dfe3-0474-5388-9006-70080842a439
DOI: 10.1101/2024.01.24.576555

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Plxnd1-mediated mechanosensing of blood flow controls the caliber of the Dorsal Aorta via the transcription factor Klf2DOI 10.1101/2024.01.24.576555Read

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