Article
Histone variants on the move: substrates for chromatin dynamics.
Nature reviews. Molecular cell biology - 1 Feb 2017
Talbert Paul B, Henikoff Steven
Abstract excerpt
Most histones are assembled into nucleosomes behind the replication fork to package newly synthesized DNA. By contrast, histone variants, which are encoded by separate genes, are typically incorporated throughout the cell cycle. Histone variants can profoundly change chromatin properties, which in turn affect DNA replication and repair, transcription, and chromosome packaging and segregation. Recent advances in...
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