Article

Targeting the Immune-Fibrosis Axis in Myocardial Infarction and Heart Failure

2022-10-21

Abstract excerpt

Cardiac fibrosis is causally linked to heart failure pathogenesis and adverse clinical outcomes. However, the precise fibroblast populations that drive fibrosis in the human heart and the mechanisms that govern their emergence remain incompletely defined. Here, we performed Cellular Indexing of Transcriptomes and Epitomes by sequencing (CITE-seq) in 22 explanted human hearts from healthy donors, acute myocardial i...

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Literature Corpus work: 5bcbb0c7-bcef-5562-a607-ff18469a22ec
DOI: 10.1101/2022.10.17.512579

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