Article

A secreted endoribonuclease ENDU-2 from the soma protects germline immortality in <i>C. elegans</i>

2020-12-04

Abstract excerpt

Multicellular organisms coordinate tissue specific response to environmental information via both cell-autonomous and non-autonomous mechanisms. In addition to secreted ligands, secreted small RNAs have recently been reported to regulate gene expression across tissue boundaries. Here we show that the conserved poly-U specific endoribonuclease ENDU-2 is secreted from the soma and taken-up by the germline to ensure...

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Identifiers and source

Literature Corpus work: 83553927-690c-5128-8122-10d1fd5baa44
DOI: 10.1101/2020.12.04.408260

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