Article

<i>jouvence</i> , a new small nucleolar RNA required in the gut extends lifespan in Drosophila

2018-10-11

Abstract excerpt

Longevity is influenced by various genetic and environmental factors, but the underlying mechanisms remain poorly understood. Here, we functionally characterise a new Drosophila small nucleolar RNA (snoRNA), named jouvence whose loss of function dramatically reduces lifespan. A transgene containing the genomic region of jouvence rescues the longevity in mutant, while its overexpression in wild-type flies increas...

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Identifiers and source

Literature Corpus work: ce48784d-9fbf-5838-852e-0817efa1fabd
DOI: 10.1101/441121

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