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Article

The roles of liver X receptor α in inflammation and inflammation‐associated diseases

10 Dec 2020

Abstract excerpt

Liver X receptor α (LXRα; also known as NR1H3), an isoform of LXRs, is a member of the nuclear receptor family of transcription factors and plays essential roles in the transcriptional control of cholesterol homeostasis. Previous in-depth phenotypic analyses of mouse models with deficient LXRα have also demonstrated various physiological functions of this receptor within inflammatory responses. LXRα activation...

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PMID: 33305467
DOI: 10.1002/jcp.30204

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