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Article

MAFB Determines Human Macrophage Anti-Inflammatory Polarization: Relevance for the Pathogenic Mechanisms Operating in Multicentric Carpotarsal Osteolysis.

Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2017

Cuevas Víctor D, Anta Laura, Samaniego Rafael, Orta-Zavalza Emmanuel, Vladimir de la Rosa Juan, Baujat Geneviève, Domínguez-Soto Ángeles, Sánchez-Mateos Paloma, Escribese María M, Castrillo Antonio, Cormier-Daire Valérie, Vega Miguel A, Corbí Ángel L

Abstract excerpt

Macrophage phenotypic and functional heterogeneity derives from tissue-specific transcriptional signatures shaped by the local microenvironment. Most studies addressing the molecular basis for macrophage heterogeneity have focused on murine cells, whereas the factors controlling the functional specialization of human macrophages are less known. M-CSF drives the generation of human monocyte-derived macrophages...

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Share to Anti-Inflammatory Agents
Share to Antigens, Differentiation, Myelomonocytic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD163 Antigen

Share to Cellular Microenvironment

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Share to Macrophage Colony-Stimulating Factor

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Source

Identifiers

PMID: 28093525
DOI: 10.4049/jimmunol.1601667

Genes

MAFB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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