Article
HBEGF <sup>+</sup> macrophages identified in rheumatoid arthritis promote joint tissue invasiveness and are reshaped differentially by medications
2019-01-31
Abstract excerpt
Macrophages tailor their function to the signals found in tissue microenvironments, taking on a wide spectrum of phenotypes. In human tissues, a detailed understanding of macrophage phenotypes is limited. Using single-cell RNA-sequencing, we define distinct macrophage subsets in the joints of patients with the autoimmune disease rheumatoid arthritis (RA), which affects ~1% of the population. The subset we refer to...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 3ef04b61-274b-5c10-b841-a5fc65254fd4
- DOI
- 10.1101/525758