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Article

Inflammation and Cancer: Extra- and Intracellular Determinants of Tumor-Associated Macrophages as Tumor Promoters.

Mediators of inflammation - 1 Jan 2017

Szebeni Gabor J, Vizler Csaba, Kitajka Klara, Puskas Laszlo G

Abstract excerpt

One of the hallmarks of cancer-related inflammation is the recruitment of monocyte-macrophage lineage cells to the tumor microenvironment. These tumor infiltrating myeloid cells are educated by the tumor milieu, rich in cancer cells and stroma components, to exert functions such as promotion of tumor growth, immunosuppression, angiogenesis, and cancer cell dissemination. Our review highlights the ontogenetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28197019
DOI: 10.1155/2017/9294018
PMCID: PMC5286482

Genes

CCL2
CXCL12
STAT1
STAT3
STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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