Article

NITRITE INCREASES MITOFUSIN-1 LEVELS TO INHIBIT VASCULAR SMOOTH MUSCLE CELL PROLIFERATION AND PREVENT INTIMAL HYPERPLASIA

2026-01-30

Abstract excerpt

<h4>ABSTRACT</h4> Vascular disease remains a leading cause of morbidity and mortality and is driven by maladaptive vascular remodeling following injury. Stent-induced vascular injury induces vascular smooth muscle cell (VSMC) phenotypic switching from a contractile to a proliferative state, resulting in intimal hyperplasia (IH), restenosis and compromised vessel function. Nitrite, an endogenous oxidation product...

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Literature Corpus work: 82df1ace-badf-5720-8ffb-f03072b55df8
DOI: 10.64898/2026.01.27.702091

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