Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Mitochondrial influences on smooth muscle phenotype.

American journal of physiology. Cell physiology - 1 Feb 2024

Pearce William J

Abstract excerpt

Smooth muscle cells transition reversibly between contractile and noncontractile phenotypes in response to diverse influences, including many from mitochondria. Numerous molecules including myocardin, procontractile miRNAs, and the mitochondrial protein prohibitin-2 promote contractile differentiation; this is opposed by mitochondrial reactive oxygen species (mtROS), high lactate concentrations, and metabolic...

Topics

Calcium
Muscle, Smooth, Vascular
Mitochondria
MicroRNAs
Myocytes, Smooth Muscle
Mitochondrial Proteins
Phenotype
Lactates

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38009196
DOI: 10.1152/ajpcell.00354.2023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial influences on smooth muscle phenotype.PMID 38009196Read ↗

Mitochondria spatially and temporally modulate VSMC phenotypes via interacting with cytoskeleton in cardiovascular diseases.Semantic proximity Read ↗

Arterial remodeling: the role of mitochondrial metabolism in vascular smooth muscle cells.Semantic proximity Read ↗

Molecular and cellular phenotypes and their regulation in smooth muscle.Semantic proximity Read ↗

Role of mitochondrial dynamics and mitophagy of vascular smooth muscle cell proliferation and migration in progression of atherosclerosisSemantic proximity Read ↗

Mitochondrial cardiovascular diseases: molecular mechanisms, multi-omics exploration and therapeutic strategiesSemantic proximity Read ↗

Exosomes: mediators regulating the phenotypic transition of vascular smooth muscle cells in atherosclerosis.Semantic proximity Read ↗

Mitochondrial dynamics, mitophagy and cardiovascular diseaseSemantic proximity Read ↗

Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular diseaseSemantic proximity Read ↗

Smooth muscle cell phenotypic modulation during atherosclerosis.Semantic proximity Read ↗

MiR-449a-5p mediates mitochondrial dysfunction and phenotypic transition by targeting Myc in pulmonary arterial smooth muscle cellsSemantic proximity Read ↗

Mitochondria in Vascular Health and DiseaseSemantic proximity Read ↗

Mitochondria in vascular diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.